About us

Reimagining drug discovery to better serve patients

Entos is disrupting drug discovery with a cutting-edge platform that integrates novel physics-informed AI design with high-throughput experimentation.  Headquartered in La Jolla, CA, the Entos team includes Nobel laureates, renowned scientists, and industry leaders in machine learning, laboratory automation, and biotechnology. Entos is advancing a pipeline of oncology therapeutics, addressing urgent patient need at the pace of program-launch-to-clinic in two years.

Join our team

Scientific and Clinical Advisory Board

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Nobel Prize. Caltech, President's Science and Tech Advisory Board, Alphabet Board of Directors.

Novartis Director of Chemical Biology Therapeutics, Author of Science “In the Pipeline” blog.

Former CSO Array BioPharma and Pfizer Boulder.

Chair of Taussig Cancer Institute, Cleveland Clinic.

CMO of Repare Therapeutics, previously Pfizer.

Scripps Research Chair of the Board of Overseers, previously ARCH Venture Partner and Celgene President of Global Research and Early Development.

Director of Hematology and Medical Oncology, NYU Langone Health.

Former head of research at Principia, Co-founder of Alumis.

USCF professor, Cofounder of Principia and Global Blood Therapeutics.

MIT Professor, autonomous discovery and machine learning.

Company Board

Entos CEO

Entos CTO

Independent Board Member

Catalio Capital

Our investors


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SVP, Business Development
VP,  chemistry
Director, Finance and Operations
VP, Clinical Operations
Exec. Director, Computational Chemistry
Exec. Director, Automation
Exec. Director, Machine Learning
VP, Analytical

Scientific advisory board

We are actively supported through our distinguished network of scientific and business advisors.

Frances Arnold

Nobel Prize in Chemistry. Linus Pauling Professor at Caltech. Member of President's Science and Tech Advisory Board and Alphabet Board of Directors.

Connor Coley

Assistant Professor of Chemical Engineering at Massachusetts Institute of Technology.

Derek Lowe

Director in Chemical Biology Therapeutics at Novartis, and author of In the Pipeline at Science Magazine.

Jack Taunton

Professor of Cellular Molecular Pharmacology at UCSF, co-founder of Cedilla, Principia Biopharma, GBT, Kezar.

Ken Brameld

Senior Advisor for Samsara Biocapital, and former SVP Head of Research, Principia Biopharma.

Nick Saccomano

Former CSO/SVP at Pfizer Boulder and former CSO, Array Biopharma.

Scientific collaborators

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Anima Anandkumar

Bren Professor of Computing at Caltech.


Collaborative discovery

We're building a diverse team of scientists and technologists to transform the discovery of small molecule therapeutics for patients with cancer.

We liberate our people to innovate, collaborate, and problem-solve. We emphasize productive communication networks, and we believe that every team member can and should play a role in helping others perform at their best.

Our core values are:

  • Innovation through collaboration and respecting different view-points
  • Continuously supporting each other to do our best work
  • Giving each person the autonomy to tackle the biggest challenges
Join our team

Headquartered in San Diego

Our headquarters and state-of-the-art laboratory facilities are located in La Jolla on the UCSD Science Research Park